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AQA A-Level Biology

A-Level · AQABiology52 notes in 9 folders, 301 KB

Notes for AQA A-Level Biology (7402), in folders for the eight topics of the specification in its order, with one note for each sub-topic or pair of sub-topics and the required practicals in the topics they belong to. A last folder covers the mathematical and practical skills the course uses. Delete the folders your course leaves out if you take AS only (the first four topics are the AS content).

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What is inside

  • Biological molecules
    • Carbohydrates and lipids9 KB
    • Proteins4 KB
    • Enzymes7 KB
    • DNA, RNA and DNA replication6 KB
    • ATP, water and inorganic ions3 KB
  • Cells
    • Eukaryotic cells, prokaryotic cells and viruses5 KB
    • Microscopy and cell fractionation6 KB
    • The cell cycle, mitosis and binary fission5 KB
    • Membrane structure and permeability5 KB
    • Transport across membranes7 KB
    • Antigens and the immune response5 KB
    • Vaccines, monoclonal antibodies, ELISA and HIV7 KB
  • Organisms exchange substances with their environment
    • Surface area to volume ratio and gas exchange in organisms7 KB
    • The human gas exchange system7 KB
    • Digestion and absorption5 KB
    • Haemoglobin and oxygen transport5 KB
    • The heart and the cardiac cycle5 KB
    • Blood vessels, tissue fluid and cardiovascular disease6 KB
    • Transport in plants7 KB
  • Genetic information, variation and relationships between organisms
    • DNA, genes and chromosomes4 KB
    • Protein synthesis4 KB
    • Mutation and meiosis6 KB
    • Natural selection and adaptation7 KB
    • Species, classification and relationships4 KB
    • Biodiversity and variation within a species5 KB
  • Energy transfers in and between organisms
    • Photosynthesis: the light-dependent reaction7 KB
    • Photosynthesis: the Calvin cycle and limiting factors5 KB
    • Glycolysis and anaerobic respiration4 KB
    • Aerobic respiration6 KB
    • Energy transfer in ecosystems and nutrient cycles8 KB
  • Organisms respond to changes in their internal and external environments
    • Plant growth factors, taxes, kineses and reflexes6 KB
    • Receptors, the retina and control of heart rate6 KB
    • Nerve impulses6 KB
    • Synapses5 KB
    • Skeletal muscle5 KB
    • Homeostasis and control of blood glucose8 KB
    • Osmoregulation and the kidney6 KB
  • Genetics, populations, evolution and ecosystems
    • Inheritance: alleles and crosses5 KB
    • Inheritance: linkage, epistasis and the chi-squared test7 KB
    • Populations and the Hardy-Weinberg principle4 KB
    • Selection, genetic drift and speciation6 KB
    • Populations in ecosystems7 KB
    • Succession and conservation5 KB
  • The control of gene expression
    • Gene mutations and protein structure4 KB
    • Stem cells and totipotency5 KB
    • Regulation of gene expression and cancer8 KB
    • Genome projects and DNA probes5 KB
    • Recombinant DNA technology7 KB
    • Genetic fingerprinting and gel electrophoresis5 KB
  • Maths and practical skills
    • Statistics and data handling6 KB
    • Calculations and graphs7 KB
    • Practical techniques and measurement7 KB

The first note

Biological molecules / Carbohydrates and lipids

## Monomers and polymers Living things are built from a small number of carbon-based molecules, and the same few building blocks turn up in every organism. A **monomer** is a small unit that can be joined to many others, and a **polymer** is the long molecule made when a large number of monomers are joined in a chain. Monosaccharides, amino acids and nucleotides are the three monomers you meet across the course. Two reactions make and break these chains. - A **condensation reaction** joins two molecules by forming a new chemical bond, and a molecule of water is released as it happens. - A **hydrolysis reaction** breaks a bond by using up a molecule of water, which is added across the bond. $$\ce{C6H12O6 + C6H12O6 <=> C12H22O11 + H2O}$$ Here two glucose molecules form maltose. The reaction runs to the right by condensation and to the left by hydrolysis. Each type of bond in the course has its own name (glycosidic, ester, peptide, phosphodiester), but the chemistry of making and breaking it is the same. ## Monosaccharides Monosaccharides are single sugar units. **Glucose**, **galactose** and **fructose** are the three to know, and each has the formula $\ce{C6H12O6}$, so they are isomers of one another: the same atoms arranged differently. Glucose exists in two forms, **α-glucose** and **β-glucose**. Both are six-carbon rings, and they differ only in the position of the hydroxyl group on carbon 1. In α-glucose the $\ce{-OH}$ on carbon 1 sits below the plane of the ring, and in…

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